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Lisez nos publications et consultez les affiches et les présentations nous avons partagées lors de conférences scientifiques. Pour toute demande concernant nos publications,  s'il vous plaît écrivez-nous . 

Publications les plus récentes
Voir le menu déroulant sous Publications et affiches pour accéder les publications plus anciennes.


An Optimized Workflow to Generate and Characterize iPSC-Derived Motor Neuron (MN) Spheroids

February 2023

Maria Jose Castellanos-Montiel et al. 

DOI: 10.3390/cells12040545

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Generation of patient-derived pluripotent stem cell-lines and CRISPR modified isogenic controls with mutations in the Parkinson’s associated GBA gene

October 2022

Carol X.-Q. Chen  et al. 

DOI: 10.1016/j.scr.2022.102919

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Systematic comparison of culture media uncovers phenotypic shift of primary human microglia defined by reduced reliance to CSF1R signaling

January 2023

Marie-France Dorion et al.

DOI: 10.1002/glia.24338


Rapid macropinocytic transfer of α-synuclein to lysosomes

July 2022

Armin Bayati et al. 

DOI: 10.1016/j.celrep.2022.111102


TDP-43 dysregulation and neuromuscular junction disruption in amyotrophic lateral sclerosis

December 2022

Sarah Lépine et al.

DOI: 10.1186/s40035-022-00331-z


Generation of homozygous PRKN, PINK1 and double PINK1/PRKN knockout cell lines from healthy induced pluripotent stem cells using CRISPR/Cas9 editing

May 2022

Carol X.-Q. Chen et al. 

DOI: 10.1016/j.scr.2022.102806


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Screening for compounds that reduce alpha synuclein fibril load in iPSC-derived neuronal cells

Andrea I. Krahn, Wolfgang E. Reintsch, Chanshuai Han, Emmanuelle Nguyen-Renou, Carol X.-Q. Chen, Wen Luo, Edward A. Fon, Thomas M. Durcan

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Characterization of the activity-dependent development of iPSC-derived neurons from Fragile X patients

Gilles Maussion, Cécilia Rocha, Vincent Soubannier, Thomas M. Durcan

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A convolutional neural network distinguishing between Parkinson's disease and healthy cells using microscopy images

Eddie Cai, Wolfgang Reintsch, Chanshaui Han, Sneha Shinde, Roxanne Larivière, Andrea Krahn, Carol X.Q. Chen, Emmanualle Nguyen-Renou, Anna Franco-Flores, Thomas M. Durcan, Edward A. Fon, Rhalena A. Thomas

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Quantitative characterization of variability in cortical neurons between healthy human induced pluripotent stem cell lines

Carol XQ. Chen, Narges Abdian, Rhalena A. Thomas, Eddie Cai, Edward A. Fon, Thomas M. Durcan, Gracia Gu

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Standardized QC workflow foranalyzing the quality and differentiation potential of human iPSCs

 Carol X-Q. Chen, Narges Abdian, Gilles Maussion, Rhalena A. Thomas, Iveta Demirova, Eddie Cai, Edward A. Fon, Thomas M. Durcan


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